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Coat slow-cooker crock with cooking spray. Stir in tomatoes, onion, carrot, garlic, oregano, sugar, salt and red pepper flakes. Crumble in ground turkey and stir to combine. Cover and cook on Low for 8 hours orHigh for 6 hours.
Stir in cream cheese and Italian seasoning until evenly incorporated into sauce. Stir half of sauce into cooked pasta; serve remaining sauce on the side. Garnish with basil, if desired.