Preheat oven to 350°F. Mix ground beef, bread crumbs, egg and seasonings in large bowl.
Shape into a loaf on shallow baking pan. Pour salsa over top.
Bake 55 to 60 minutes or until meat loaf is cooked through. Let stand 5 minutes before serving.
Substitution Tip: Prepare as directed, using 1 teaspoon McCormick® Garlic Salt in place of the garlic powder and salt.
Sprinkle cooked meat loaf with shredded Mexican blend cheese. Let stand 5 minutes before slicing.